The Freimann Life Science Center (FLSC) is home to virtually all laboratory animals supporting Notre Dame teaching and research. Since the founding of this center in 1983, it has been the University's goal to maintain an exemplary facility.

The FLSC was originally designed to meet the needs of the biology faculty with major research interests in parasitology and vector biology. Today, the FLSC primarily serves faculty from the Departments of Biological Sciences, Chemistry and Biochemistry, Chemical Engineering and the Indiana University School of Medicine - South Bend.

The Center houses a wide variety of vertebrates, primarily rodents but also fish (including a large zebrafish population), rabbits and frogs. The FLSC has the capabilities to house a variety of laboratory animals such as mini pigs, guinea pigs, birds, dogs, cats and a variety of wild animals. A transgenic mouse colony housing over 100 different strains is maintained at the facility. The National Cancer Institute's approved model for prostate cancer, the LOBUND-Wistar rat, was developed at Notre Dame and continues to be maintained at FLSC.

The Freimann Life Science Center is fully accredited by AAALAC International. The Center is also inspected annually by the United States Department of Agriculture and adheres to the Animal Welfare Act.